Norlina Ramli, Mimiwati Zahari, May May Choo
Department of Ophthalmology, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia

A 22-year-old woman presented with a 2- to 3-day history of positive scotomas in both eyes, preceded by a 2-week episode of influenza-like symptoms, sore throat, and erythema nodosum. Ocular examination revealed multiple pale yellow lesions at the level of the retinal pigment epithelium in both eyes. Fluorescein angiogram confirmed features of acute multifocal posterior placoid pigment epitheliopathy with early hypofluorescence and late hyperfluorescence over the lesions. Blood test revealed raised antistreptolysin O titre and erythrocyte sedimentation rate. This report highlights that patients with acute multifocal posterior placoid pigment epitheliopathy may have a significant systemic disorder associated with the ocular findings.

Key words: Acute multifocal posterior placoid pigment epitheliopathy, Antistreptolysin, Erythema nodosum, Pigment epithelium of eye, Streptococcus

Asian J Ophthalmol. 2008;10:136-139.